The American Hairless Terrier is a smoothly muscled, active, smallest to small terrier. The preferred ratio of length of body (prosternum to point of buttocks) to height (withers to ground) to is 10:9. The head is broad, slightly domed, wedge-shaped, and proportionate to the size of the body. Ears are V-shaped, set at the outside edges of the skull, and may be erect, tipped or button. Both varieties may have a natural tail carried in an upward curve, or the tail may be docked in dogs of the coated variety. The American Hairless Terrier comes in a number of skin colors and patterns (hairless variety) and coat colors and patterns (coated variety).

The American Hairless Terrier is an energetic, alert dog whose curiosity and intelligence make him easy to train. The ancestors of this breed were bred to hunt. The lack of coat makes the hairless variety unsuited for hunting, but both varieties still have a strong hunting instinct and the coated dogs are fearless, tenacious hunters with seemingly unlimited energy. The American Hairless Terrier is an exceptionally friendly companion, getting along well with children, other dogs, and even cats. American Hairless Terriers enjoy human companionship immensely and will enthusiastically share any activity with their owners. The hairless dogs require protection from the sun and winter cold weather. American Hairless Terriers should not be sparred during conformation judging.