The American Shorthair is known for its longevity, robust health, calm disposition, good looks, friendliness and gentleness. It is a true native American breed that comes in a variety of colors, although it does not come in a pointed pattern like that of the Siamese. The best known American Shorthairs are the dramatically marked silver tabbies, which have been popular in commercial advertisements and movies.

The American Shorthair ranges in size from medium to large. It is well-built and powerful, with a short, dense coat and large, piercing round eyes. This breed is less square in shape and larger than its counterpart, the British Shorthair. It also has a more oblong rather than a round head, larger ears and longer legs. This is a low-maintenance breed that only requires occasional brushing to keep its coat fresh and manage mild shedding.